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KMID : 0380020070220060409
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Korean Journal of Biotechnology and Bioengineering
2007 Volume.22 No. 6 p.409 ~ p.413
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Polydiacetylene-Based Chemo-/Biosensor of Label Free System with Various Sensing Tools
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Chung Bong-Hyun
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Abstract
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Polydiacetylene(PDA)-based sensors possess a number of properties that can be successfully applied for label-free detection system. PDA is one of the most attractive color-generating materials, with growing applications as sensors. Here we introduce various PDA-based devices, used as biosensor, chemosensor, thermosensor, and optoelectronics sensor. In general, PDA liposomes and films are closely packed and properly designed for polymerization via 1,4-addition reaction to form an ene-yne alternating polymer chain. PDA-based two/three dimensional structures have been used for colorimetric or fluorescent devices, sensing biological as well as chemical components. This color-generating material also present a very high charge carrier mobility, allowing its application as field-effect transistor (FET). The immobilized PDA structures or films have distinct advantages for the detection of low concentration target molecules over the aqueous solution-based detection systems. In the present review, reported detection methods by using various PDA structures are summarized with updated references.
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KEYWORD
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Polydiacetylene, biosensor, chemosensor, liposome, PDA-FET
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